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This process is exacerbated by telomere shortening, which occurs naturally with age but can be accelerated by oxidative stress and environmental factors, leading to cellular senescence and decreased melanocyte function

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Metabolic Changes in Acute Undernutrition and Obesity Despite being on distinctive ends of the nutrition spectrum, acute undernutrition and obesity in childhood both trigger devastating and often intersecting endocrine maladaptations

Chromosome Segregation in the Oocyte: What Goes Wrong during Aging

Trejo CG, Lozano D, Manzano M, Doadrio JC, Salinas AJ, Dapia S, et al